3_12_09_RewardAndAddiction

3_12_09_RewardAndAddiction - Outline of the Lecture Outline...

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Unformatted text preview: Outline of the Lecture Outline of the Lecture Reward and Addiction Reward and Addiction Temporal Difference Learning Model of Temporal Difference Learning Model of Addiction Addiction The Temporal-difference The Temporal-difference Model Accounts for Model Accounts for Reinforcement Learning Reinforcement Learning and Addiction and Addiction Unsupervised learning is self-organization to maximize extraction of information from input. One way is by having a supervisor tell the network whether its performance is good. Classical conditioning is an implicit-memory learning dependent on stimuli correlations. dependent on stimuli correlations. Pavlov showed that classical conditioning can occur with both rewards and punishments. Prefrontal Cortex Nucleus Accumbens Ventral Tegmental Area Reward mechanisms involve the prefrontal cortex, the nucleus accumbens, and the VTA. The role of the dopaminergic VTA neurons appears to be getting reward-prediction error. In delayed-reward experiments, VTA neurons first respond only to reward; later, they respond to stimuli, showing suppression without reward. The VTA-nucleus-accumbens circuitry also mediate the mechanisms of addiction. Cocaine and nicotine affect the rate of electrical self-stimulation of the brain. In Temporal Difference learning, we use a discrete time variable t...
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This note was uploaded on 06/08/2009 for the course BME 575L taught by Professor Grzywacz during the Spring '09 term at USC.

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3_12_09_RewardAndAddiction - Outline of the Lecture Outline...

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