BME 552 - Class I 2009

BME 552 - Class I 2009 - Class I BME 552 Neural Implant...

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1 Class I BME – 552 Neural Implant Engineering January 16, 2009 Overview of Today’s Class • Introductions • Preview of class, Exams, Projects • Learning Objectives • Brief History of Electrical Stimulation • Current Clinical Systems • Grand Challenges in Neural Implant Design • Neuroscience review
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2 Today’s Material • Class slides • 1 article (cochlear implants) • Syllabus All class material will be available on blackboard by noon Thursday prior to class http://den.usc.edu/ Preview of Class (review syllabus) • Homework – 20% (about 1 each class) • Exams 1 and 2 – each 25% Exams 1 and 2 each 25% • Class participation – 10% – Answering questions in class – Come to class with 1 question from reading – Paper review (majority of this grade) • Project – 20% Experimenta – Experimental –Des ign – Modeling – Critical Review
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3 Cross campus class • UC Santa Cruz students are participating via DEN and phone call in • Some pre-recorded, remote lectures (exact format in progress) • Grades are assigned separately between the campuses Preview of Class • Each class will require you to read a paper(s) prior to class references paper(s) prior to class, references available, you should be able to download via library • Lecture and HW will refer to readings • Lecture will review basics and/or latest research in a particular area related to neural implant engineering. • Review syllabus
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4 Survival Guide for BME 552 • Lots of reading involved • Multiple instructors will have different approaches (I will attend most lectures for continuity) • Review neuroscience (neurons structure, synapse, glia cells, action potential generation) • Circuit elements: Z R ( ω ) = R, Z L ( ω ) = j ω L, Z C ( ω ) = 1/(j ω C) Learning Objectives • Evolution of electrical stimulation – Then Crude devices coupled with little – Then - Crude devices coupled with little understanding of biology – Now – Better engineering and more scientific knowledge • State-of-the-Art in – Cochlear implants Prosthetic Arms – Prosthetic Arms • Unsolved challenges for future devices (visual, cortical) • Neuroscience Review
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5 History of Electrical Stimulation • Very early clues about interaction of electricity with the human body • Early electrically active implantables • The cochlear implant • Prosthetic arm Fables of Electrical Stimulation • Romans used electric eels from the Mediterranean Sea to treat headaches • Several scientists in the 18 th , 19 th , and early 20 th century investigated electrical stim of the nervous system
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6 LeRoy’s electrical stimulation of a blind person - 1755 • Brass wire wound around the head • Return electrode attached to right leg • Blind subject saw a “flame rapidly descending” descending Volta and Galvani • Stimulation of muscle in frogs • Volta stimulated his ears with electrode, noted a “bubbling” sound
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7 Many other examples • Many tests/experiments in 19 th
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BME 552 - Class I 2009 - Class I BME 552 Neural Implant...

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