BME_552_2007_lecture2_Berger_neurosci_part1

BME_552_2007_lecture2_Berger_neurosci_part1 - BME 552...

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Unformatted text preview: BME 552 Neural Implant Engineering Fundamental Neuroscience I Bioelectric Properties of Neurons- Basis of the membrane potential membrane structure barriers to transmembrane ion diffusion intra/extracellular ion concentration differences role of ion pumps, transporters- Channels mechanisms for transmembrane current channel selectivity concentration and electrical gradients equivalent circuit model conductance and permeability I-V relationships BME 552 Lecture 2 Bioelectric Properties of Neurons (cont.)- Passive membrane properties membrane resistance ion mobility through membrane and axoplasm r m and r i length constant, spatial summation specific membrane resistance membrane capacitance dielectric property of the membrane time constant, temporal summation functional consequences of cell morphology BME 552 Lecture 2 Bioelectric Properties of Neurons (cont.)- Basis of the action potential regeneration; all-or-none potential voltage clamp analysis dissociation of Na + and K + currents voltage-dependence of Na + and K + activation voltage- and time-dependence of (Na + ) inactivation Hodgkin-Huxley parameters...
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This note was uploaded on 06/08/2009 for the course BME 552 taught by Professor Berger,weiland during the Spring '09 term at USC.

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BME_552_2007_lecture2_Berger_neurosci_part1 - BME 552...

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