Lecture 14, Calcium and Hormones

Lecture 14, Calcium and Hormones - BCH 120/BMD 120 Spring...

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BCH 120/BMD 120 Spring 2008 Outline for Lecture #12 Ca 2+ Hormones I. Calcium and Phosphorus A. Ca 2+ B. Phosphorus (P i ) C. Blood Ca 2+ and P i D. Bone 1. Skeletal functions 2. Bone categories 3. Skeletal components 4. Bone cells 5. Skeletal mineral compartments 6. Calcium dynamics
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ASSIGNED READING FOR DISCUSSION SECTION ASSIGNED READING FOR DISCUSSION SECTION A.W. NORMAN Tuesday, April 29, 2008 Clinical Correlate on Osteoporosis : Your assignment for Discussion on THURSDAY, May 3rd is to read the following two (2) papers on osteoporosis that are available for download on http://ilearn.ucr.com… 1. New England Journal of Medicine New England Journal of Medicine , , 326: 326: 357 357 -362 (1992) 362 (1992) “Treatment of postmenopausal osteoporosis with calcitriol of calc Treatment of postmenopausal osteoporosis with calcitriol of calc ium ium 2. New England Journal of Medicine New England Journal of Medicine , , 338: 338: 485 485 -492 (1998) 492 (1998) “Prevention of bone loss with alendronate in postmenopausal women Prevention of bone loss with alendronate in postmenopausal women under 60 years of age under 60 years of age
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BIOLOGICAL CALCIUM AND PHOSPHORUS
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IMPORTANT!!! P is for phosphorus NOT phosphate
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Manifestations of Hypercalcemia Acute Chronic Gastrointestinal Anorexia, nausea, vomiting Dyspepsia, constipation, pancreatitis Renal Polyuria, polydipsia Nephrolithiasis, nephrocalcinosis Neuro-muscular Depression, confusion, stupor, coma Weakness Cardiac Bradycardia, first degree atrio-ventricular Hypertension block, digitalis sensitivity
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I. Calcium and Phosphorus A. Ca 2+ B. Phosphorus (P i ) C. Blood Ca 2+ and P i D. Bone 1. Skeletal functions a. Mechanical support b. Metabolic functions - help maintain a steady state of ionic constituents.
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This note was uploaded on 06/08/2009 for the course BCH 120 taught by Professor Luben,norman,henry during the Spring '09 term at UC Riverside.

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Lecture 14, Calcium and Hormones - BCH 120/BMD 120 Spring...

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