lec10 - fig19-27 an ancient mode of ATP production...

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fig19-16 (simplified) electron transport chain
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fig19-17
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proton-motive force
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the coupling question… chemiosmotic hypothesis!
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fig19-19
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fig19-20
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weak acid uncouplers
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fig19-21 Weak acid uncouplers
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fig19-21 Chemical uncouplers
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fig19-21 Chemical uncouplers
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Chemical uncoupler experiment fig19-20
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Proton gradient experiment fig19-22
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ATP synthase: the F1 subunit
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fig19-23 ATP and ADP are in rapid equilibrium in the F1 ATPase
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Energetics of ATP and ADP in F1 ATPase… fig19-24
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fig19-25 The “binding-change” model for ATP synthase
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fig19-25 The “binding-change” model for ATP synthase
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fig19-26 The “binding-change” model for ATP synthase
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fig19-25 The F complex of the ATPase…
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The F F complex fig19-25
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Unformatted text preview: fig19-27 an ancient mode of ATP production Bacterial generation of H+ gradient by respiratory chain “There’s more than one way to shrink a gradient…” fig19-39 Inner membrane translocases (or transporters) fig19-28 eeeeek! Malate-aspartate shuttle fig19-29 NADH NAD + Malate-aspartate shuttle Malate-aspartate shuttle Glycerol 3-P shuttle fig19-30 Nature’s electric blanket fig19-34 thermogenin regulation of ATP producing pathways fig19-33 regulation of ATP producing pathways fig19-33 fig19-33 regulation of ATP producing pathways remnants of a once-independent genome. .. fig19-39 Leber's hereditary optic neuropathy mitocondrial disease genetics fig19-39 myoclonic epilepsy and ragged-red fibre disease mitocondrial disease genetics myoclonic epiliepsy and ragged-red fiber disease (MERRF) fig19-39...
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