04 - MIC170 Lecture 4(Thursday 4/9 Yeast Cell 5 Cytoskeleton continued A Actin B Tubulin Heterodimer of and tubulins(~50 kDa each polymerize to

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MIC170 – 4/9/09 1 Lecture 4 (Thursday, 4/9) Yeast Cell - 5. Cytoskeleton, continued A. Actin B. Tubulin Heterodimer of α and β tubulins (~50 kDa each) polymerize to form microtubules Fig. 12.42 from Textbook ----> yeast tubulins have 75% identical amino acid sequence to human tubulins “dynamic instability” in living cells, each microtubule elongates and shrinks very rapidly due to continuous polymerization/depolymerization (movie) Fig. 12.44 from the textbook Microtubule Function: i) Forms spindle that separate chromosomes in mitosis (appears to be the most important function) ii) Nuclear positioning at the bud neck before mitosis ---- Fig. 2 in handout-KS3
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MIC170 – 4/9/09 2 Yeast Life Cycle We’ll look at the life cycle of the budding yeast S. cerevisiae (Fig. 4.19, handout-4) Developmental options in budding yeast A. Vegetative growth Haploid (DNA content = 1n) or diploid (2n) B. Stationary phase C. Mating --- two haploid cells of different mating types ( a and α ) conjugate and form diploid D. Meiosis and sporulation--- diploid cells form four haploid (1n) spores
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This note was uploaded on 06/11/2009 for the course MIC 170 taught by Professor Shiozaki during the Spring '09 term at UC Davis.

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04 - MIC170 Lecture 4(Thursday 4/9 Yeast Cell 5 Cytoskeleton continued A Actin B Tubulin Heterodimer of and tubulins(~50 kDa each polymerize to

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