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Genetics Test 1 study guide - ● ● ● ● ● What is a gene? ○ A...

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What is a gene?A single unit with a complex function, there is about 25,000 genes in a humanGenetics in the news and in you lifeGenetic testing-23andMeAnimal conservation-Taz endangered, they eat dead things, found to have adisease that affected their faces, (devil facial tumor disease) which is a mutationfrom DNA from the nervous cells.It started from 1 taz developed the tumor, then fought another animal, thecells were then transferred and developed a tumor and it was past on andtransferred.Genetics of diseaseLynch Syndrome-inherited colon cancer that only affects 2-4%. 2 genesMLH1andMSH2.MLH1 protein fixes mismatch and MSH2 protein finds the mismatchNucleic acid chemistry/nucleotide componentsA (adenine) present in both DNA/RNAT (thymine) present in DNAG (guanine) present in bothC (cytosine) present in bothU (uracil) present in RNAWithin the sugar ribose(OH) and deoxyribose(H)Phosphate group- mono, di, triStructure DNA/RNA differencesPyrimidineis smaller (C, U, T)DNADNA larger molecule with smaller subunitsAmino acid = proteinsPurineis a double ring structure (A & G)DNA is copied during(S)phase, and needs to be untwisted(DNApolymerase)Protein synthesis, occurs one gene at a time is used for transcription of agene (RNA synthesis)Phosphodiester bondsCovalent bond linking two 5’ to 3’ bondsWatson and CrickThe structure of the DNAForm = functionEnvironmental conditions like temperature5’ is phosphate3’ is OH5’ to 3’ = carbon moleculeA-T 2 bondsG-C 3 bondsBase pairsDouble helix
Structure-Total of 2 nm in diameterDistance between two base pairs is 0.34 nm or3.4 Angstroms(10 to the-10)Pairs are perpendicular to the axis1 complete loop = 3.4 nm per turn or34 Angstroms.There is10 pairs perturn.

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Term
Spring
Professor
Ann Zeeh

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