Chapter 9 - Chapter 9 Proteins and Their Synthesis...

Info icon This preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 9: Proteins and Their Synthesis I) Functional RNAs important in protein synthesis A) tRNA—translate three-nucleotide cogon in mRNA into corresponding amino acid B) rRNA—major components of ribosomes, assemble amino acids to form protein whose sequence is encoded in a specific mRNA C) make up largest fraction of total cellular RNA 1) More stable than mRNAs 2) Transcription of these constitutes >1/2 of all transcription II) Proteins—main determinates of biological function and form A) Composed of amino acids 1) Have side chain (Reactive (r) group) 2) Linked together by peptide bonds between the amino end of one and the carboxyl end of another B) Four levels of structure 1) Primary structure—linear sequence of amino acids 2) Secondary structure—local regions of polypeptide folding (most common are α helix and the pleated sheet) 3) Tertiary structure—folding of secondary structure 4) Quaternary structure—some proteins, subunits that are composed of 2+ separate folded polypeptides joined by weak bonds C) Types 1) Globular proteins—compact structures including enzymes and antibodies 2) Fibrous proteins—linear shape, in skin, hair, tendons D) Specific shape allows it to do its specific job in a cell, determined by primary structure and conditions in cell E) Domains—amino acid sequences or conserved protein folds associated with particular functions F) Colinearity--Linear correspondence b/t nucleotides in DNA and amino acids in protein III) Genetic code A) Overlapping v. nonoverlapping codes 1) Nonoverlapping—consecutive amino acids specified by consecutive codons 2) Overlapping—consecutive amino acids specific by codons that have some consecutive bases in common 3)
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern