Chapter 6 - Chapter 6: Gene Interaction I) Genes act by...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 6: Gene Interaction I) Genes act by controlling cellular chemistry A) Mutations can causes defects in metabolism (general set of chem. . reactions in organism) B) One-gene-one-polypeptide hypothesis: a gene encodes the physical structure of a protein, which dictates its function--Affect function of enzymes C) Gene interaction in synthetic pathways (chain of enzymatic conversions that creates essential nutrients) II) Inferring gene interactions A) Treat cells with mutation causing agents—confirm single-gene inheritance B) Test mutants to determine total number of gene loci taking part and which mutations are alleles on the same gene. Done through Complementation test— determine if two mutations belong to same gene 1) Can only be applied to recessive mutations 2) Cross two homozygous mutant lines to produce heterozygote a) If wild-type—mutations complement one another and are on different genes (Complementation—production of wild-type phenotype when two haploid genomes bearing diff. recessive mutations are united in same cell)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/01/2008 for the course ZOL 341 taught by Professor Dworkin during the Spring '08 term at Michigan State University.

Page1 / 2

Chapter 6 - Chapter 6: Gene Interaction I) Genes act by...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online