PPK PENYAKIT PARKINSON.docx - STATUS EPILEPTIKUS...

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PANDUAN PRAKTIK KLINIK Tanggal Terbit 2018 Ditetapkan dr. Hj. Umi Aliyah, M.Kes. Direktur Pengertian Penyakit Parkinson adalah bagian dari Parkinsonism yang patologis ditandai dengan degenerasi ganglia basalis terutama di pars compacta substansia nigra disertai dengan inklusi sitoplasmik eosinofilik ( Lewy's bodies ). Parkinsonism adalah sindroma yang ditandai dengan tremor waktu istirahat, rigiditas, bradikinesia dan hilangnya releks postural akibat penurunan dopamin karena beberapa sebab. Anamnesis Umum: - Gejala dimulai pada satu sisi (Hemiparkinson). - Tremor saat istirahat. - Tidak didapatkan gejala neurologis lain. - Tidak dijumpai kelainan laboratorium dan radiologi. - Perkembangan penyakit lambat. - Respon terhadap Levodopa cepat dan dramatis. - Refleks postural tidak dijumpai pada awal penyakit. Khusus : - Tremor : laten, saat istirahat, bertahan saat istirahat. - Rigiditas. - Akinesia/bradikinesia. - Kedipan mata berkurang. - Wajah seperti topeng.
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