Ligamiento (3).pptx - CHROMOSOME MAPPING Linkage Linkage equilibrium Linkage disequilibrium • Interlocus distance The frequency of crossing over

Ligamiento (3).pptx - CHROMOSOME MAPPING Linkage Linkage...

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CHROMOSOME MAPPING Linkage Linkage equilibrium Linkage disequilibrium
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Interlocus distance : The frequency of crossing over between any two loci on a single chromosome is proportional to the distance between them.
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Such a 1:2:1 ratio is characteristic of complete linkage .
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Morgan/Stutervand mapping
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Morgan was faced with two questions: What was the source of gene separation Why did the frequency of the apparent separation vary depending on the genes being studied?
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Mapping Chromosome map of the three genes on the X chromosome, setting one map unit (mu) equal to 1 percent recombination between two genes.
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Single Crossovers
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Single Crossovers Even if a single crossover occurs 100 percent of the time between two linked genes, recombination is subsequently observed in only 50 percent of the potential gametes formed .
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Single Crossovers
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Three-Point Mapping in Drosophila To execute a successful mapping cross, three criteria must be met: – The genotype of the organism producing the crossover gametes must be heterozygous at all loci under consideration. If homozygosity occurred at any locus,
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  • Fall '19
  • • Morgan

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