Anemias.docx - Condition which hemoglobin is lower than normal reflects presence of fewer than normal erythrocytes results in diminished amount of O2

Anemias.docx - Condition which hemoglobin is lower than...

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Condition which hemoglobin is lower than normal, reflects presence of fewer than normal # erythrocytes results in diminished amount of O2 delivered to body tissue. Not a specific disease but sign of underlying disorder Classification of Anemias: a. Hypoproliferative (defective production) i. marrow damage due to meds: chloramphenicol ( treat serious bacterial infections ii. Lack of factors necessary for erythrocyte formation 1. Iron Deficiency Megaloblastic 2. Vitamin B12 Megaloblastic 3. Decreased erythropoietin production renal dysfunction ( hormone produced primarily by the kidneys) 4. Cancer/inflammation b. Bleeding (Resulting from RBC loss) i. GI bleed ii. Epistaxis iii. Trauma iv. Genitourinary tract: menorrhagia c. Hemolytic (RBC Destruction) i. Liberation of Hgb from erythrocytes into plasma = increased bilirubin ii. Destruction leads to hypoxia = stimulates production = increase reticulocyte (immature RBCs) 1. Inherited Hemolytic Anemias 2. Altered Erythropoiesis: Sickel Cell disease = Abnormality
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  • Fall '17
  • MR.HACK
  • Hemoglobin

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