mol_biol_slides

mol_biol_slides - Introduction to Biochemistry Molecular...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
Introduction to Biochemistry Molecular Biology Structural Properties of DNA and RNA A base - either purine or pyrimidine A sugar - ribose in RNA, deoxyribose in DNA One or more phosphoryl groups Nucleotide building blocks include: Purine Bases
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Pyrimidine Bases Phosphodiester Bond Basic Principles Replication : the process in which DNA is copied Transcription : the process in which m-RNA is synthesized Translation : the process in which proteins are synthesized Complementarity : A=T G=C
Background image of page 2
Hydrolysis of Phosphodiester Bonds Non-specific : deoxyribonucleases (DNases) Specific: restriction endonucleases Restriction Consider two different strains of E. coli Usually, the introduction of DNA from one strain into the other strain results in hydrolysis of the foreign DNA Modification When foreign DNA is not degraded, it is because it has been modified in a pattern identical to that of the host strain Modification consists of methylation (-CH3) of some bases
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/01/2008 for the course BCHM 1014 taught by Professor Tositz during the Fall '07 term at Virginia Tech.

Page1 / 10

mol_biol_slides - Introduction to Biochemistry Molecular...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online