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1414-04 Fluids Electrolytes 2019bb.pptx - HOMEOSTASIS OF...

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HOMEOSTASIS OFFLUIDS &ELECTROLYTESHOMEOSTASIS OFFLUIDS &ELECTROLYTES
Learning ObjectivesDescribe the movement of fluid between fluidcompartmentsOutline Starling’s Law…important**Describe the regulation of fluid balance including ADHand RAASDifferentiate between 4 causes of edema and thedifferent tonicities of solutionsIdentify key features of some important electrolytes andtheir imbalances
HomeostasisThe ability of the body tomaintain a relativelyinternalenvironment
Need for water andelectrolyte balancehomeostasis of cells dependsupon homeostasis of bodyfluids and electrolytes
all water and dissolvedsubstances in the body’s fluidcompartmentsBody fluids
total volumedistributionconcentration ofsolutespHMechanisms Regulate
Body Weight Distribution40% solids60% liquids(total body water)55% liquids45% solidsmalesfemales
Major fluidcompartments
Fluid CompartmentsIntracellular Fluidinside cellscytoplasm
Fluid CompartmentsCellsIntracellularfluid(ICF)(ICF)(ICF)(ICF)(ICF)Extracellular FluidBloodinterstitalFluidintravascularFluidTranscellulaFluid
Bodyextracelluar Fluidintracellular Fluidintercelluar FluidIntertisitialFluidtranscellualr FluidFluid Compartments
Body Weight Distribution40%20%16 %4%
Composition ofBody FluidsCellsBloodCl-HPO42-Protein-Cl-Cl-HCO3-HCO3-Protein-NaNaKNaK+K+
ICF has moreK+and proteinECF has moreNa+ , Cl-, HCO3-composition of plasma andinterstitial fluid is similarComposition ofBody Fluids
Composition ofBody FluidsCellsBloodNa+Cl-HPO42-Protein-K+Na+Na+Cl-Cl-K+K+HCO3-HCO3-Protein-‘Plasmaproteins’Primaryone is
Movement of water betweenfluid compartmentsexchange between compartmentsoccurs in only two places:through cellmembranes(exchangebetween ICFand interstitialfluid)throughcapillary walls(exchangebetweeninterstitial fluidand plasma)
Interlude-TransportProcessesmay beactiveorpassivehsph.harvard.educurunam.org
Passive TransportProcessesno metabolicenergy requiredsubstances move along theirconcentration gradientsdriven bydiffusion pressure
Simple Diffusionmovement of molecules fromarea ofhigherconcentration toan area of lower concentrationconcentrationstaff.rentonschools.us
Osmosismovement ofwater moleculesthrougha selectively permeable membranefrom area of higherwaterconcentration to an area of lower waterconcentration

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