PICOT STATEMENT WITH RESEARCH CRITIQUES2Healthcare-associated infections (HAIs) are a serious healthcare problem that is very prevalent today. A healthcare-associated infection is an infection that a patient has developed within at least 48-72 hours as a result of being in a healthcare facility and receiving medical treatment, and these infections are often preventable by healthcare professionals. Healthcare-associated infections are a Healthy People 2020 topic with a goal of prevention, reduction, and elimination. HAIs are a direct result from procedures, surgery, central line associated bloodstream infections, urinary catheter associated infections, surgical site infection, ventilators, Methicillin- resistant Staphylococcus aureus (MRSA), and pneumonia, which can all be life threatening. HAIs are a pressing healthcare problem because it is a huge patient safety concern asthey are a major cause of patient morbidity and mortality in the United States.In 2011, an estimated 648,000 patients experienced 721,800 HAIs in United States acute care hospitals (Huang, Chen, Wang, & He, 2016). Recent studies suggest that implementing existing prevention practices such as prevention bundles and chlorhexidine bathing can lead to up to a 70 percent reduction in certain HAIs with a financial benefit estimated to be $25 billion to $31.5 billion in medical cost savings (Office of Disease Prevention and Health Promotion [ODPHP], 2019). Research concerning CHG bathing intervention was evaluated and found to decrease HAIs, and reduction was greater than compared to bathing with soap and water (Rubin, Louthan, Wessels, Downer, & Maiden, 2013). As we know interventions only work with education and compliance. Education about CHG bathing, proper application, and compliance are key to preventing HAIs and it starts with staff knowledge. This paper will present my PICOT question, my research critiques of two qualitative and quantitative articles related to PICOT question, and the proposed evidence-based practice change.