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Unformatted text preview: LESSON PLAN: STEM CELL RESEARCH: THE DEBATE OVER EMBRYONIC AND
ADULT STEM CELL USE Emily Heller
Name: ______________________________________ 8/27/2019
Date: _____________ Fact Finding Worksheet
Directions: Working in pairs or small groups, use library and internet resources to learn as much
as you can about stem cell research and current stem cell based therapies. When answering
questions, be sure to document your information sources like all good scientists do. Use
additional paper if you run out of space for answering a specific question. Be prepared to share
what you have learned with your classmates. All group members must complete their own copy
of the worksheet for use on a later project.
1. What is the definition of a stem cell?
An undifferentiated cell of a multicellular organism which is capable of giving rise to indefinitely more cells of the same type, and from
which certain other kinds of cell arise by differentiation. Source: Online Oxford dictionary
2. What is the difference between adult stem cells and embryonic stem cells?
Adult stem cells are limited and embryonic stem cells become all cell types of the body. Source: 3. What is a blastocyst?
a mammalian blastula in which some differentiation of cells has occurred. Source: Online Oxford dictionary
4. What parts of the human body contain stem cells?
Many organs ad tissues, including brain, bone marrow, perpheral blood, blood vessels, skeletal muscle, skin, teeth, heart, gut, liver,
ovarian epithelium, and testis.
Source: 5. What is a stem cell line?
A stem cell line is essentially a group of stem cells that is cultured for various purposes using in-vitro methods. Source:
1 6. In what ways might the use of embryonic stem cells be better than the use of adult stem cells?
Embryonic stem cells are capable of almost unlimited division, when placed in a culture whereas adult stem cells do not multiply
so readily. Source: 7. In what ways might the use of adult stem cells be better than the use of embryonic stem cells?
One major difference between adult and embryonic stem cells is their different abilities in the number and type of differentiated cell
types they can become. Source: 8. How can stem cells be used to treat diseases and injuries? List current uses.
In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease or serve as a way for the donor's immune
system to fight some types of cancer and blood-related diseases, such as leukemia, lymphoma, neuroblastoma and multiple myeloma. Source:
9. What are some of the current experimental ways that stem cells are being used to treat disease
replace neurons damaged by spinal cord injury, stroke, Alzheimer's disease, Parkinson's disease or other neurological problems;
produce insulin that could treat people with diabetes and heart muscle cells that could repair damage after a heart attack. Source:
10. Why is there controversy about using embryonic stem cells?
The stem cell controversy is the consideration of the ethics of research involving the development, use, and destruction of human
embryos. Most commonly, this controversy focuses on embryonic stem cells. Source:
11. Why has government funding for stem cell research been limited?
US government funding for research using embryonic stem cells has been thrown into disarray after a judge ruled that it violates laws
prohibiting the destruction of human embryos. Source: 2 12. Describe the process used for harvesting embryonic stem cells.
Traditionally, embryonic stem cells were harvested by destroying the human embryo in a process called somatic cell nuclear transfer
(SCNT). Source: 13. Describe the process used for harvesting adult stem cells.
When blood stem cells are collected from the bloodstream, the procedure is called a peripheral blood stem cell collection or harvest. Source: 14. Describe the process of using adult stem cells to treat a specific disease.
The first stem-cell-based therapy was a bone marrow transplant used to treat leukemia. In this procedure, the patient's existing bone
marrow is destroyed by radiation and/or chemotherapy. Donor bone marrow is injected into the patient and the bone marrow stem cells
establish themselves in the patient's bones. Source:
15. Describe what type of human tissues, organs, or other cells have been grown from human
Adult stem cells have been identified in many organs and tissues, including brain, bone marrow, peripheral blood, blood vessels,
skeletal muscle, skin, teeth, heart, gut, liver, ovarian epithelium, and testis. Source: 16. List all other interesting facts, examples, or data you learned about stem cell research. List
the source after each item.
You are a collection of over 30 trillion human cells. Every one of these cells, those in your brain, lungs, liver, skin, and everywhere else,
derives from a single pluripotent type of cell called a stem cell. 3 ...
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- Fall '19
- Shelley Stoner
- Cellular differentiation