Detecting Inherited Forms of Cancer.docx - Running head GEL...

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Running head: GEL ELECTROPHORESIS 1 Gel Electrophoresis Madison English W.P. Davidson High School January 16, 2019
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GEL ELECTROPHORESIS 2 Abstract HNPCC (hereditary non-polyposis colorectal cancer) is a type of colorectal cancer. The colon and rectum, which are parts in the digestive system, removes water and electrolytes from food that has been digested so that it can make and store solid waste until it goes out of the body. Colon cancer is a type of cancer that begins in the colon, and rectal cancer begins in the rectum. Colorectal cancer is an alternative name for cancers that affect either of those organs. Lynch syndrome (a.k.a. HNPCC) can result in an abnormal growth of the colon, which may become cancerous. Approximately 3% of people who have colon cancer have HNPCC. In the U.S. there are about 160,000 new HNPCC cases every year and when mutated, there are four genes that cause the cancer. The four genes that cause HNPCC are called “caretaker genes.” Caretaker genes help repair the DNA mutations by scanning the genome. If two copies of a certain caretaker are mutated then HNPCC will occur. Inheriting this mutation in an HNPCC gene does not mean cancer will form, but there is an 80% risk during his/her lifetime of getting colorectal cancer. The earlier the symptoms of colon cancer are detected, the
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