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1 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Doç. Dr. Nizamettin AYDIN [email protected] Introduction to Bioinformatics
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2 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Recommended Texts
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3 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Recommended Texts - 2
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4 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Recommended Texts - 3
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5 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Recommended Texts - 4 Bioinformatics for Dummie s Jean Claverie, Cedric Notredame Bioinformatics: A Practical Guide to the Analysis of G enes and Proteins Andreas D. Baxevanis, B. F. Ouellette, Ouellette B. F. Francis. Instant Notes in Bioinformat ics D. R. Westhead, Richard M. Twyman, J. H. Parish Bioinformatics: Sequ ence and Genome Ana ysis, Vol. 5 David W. Mount, David Mount Developing Bioinform atics Computer Skill s Cynthia Gibas, Per Jambeck, Lorrie LeJeune (Editor) Discovering Genomics, Proteomics, and Bioinformatics A. Malcolm Campbell, Laurie J. Heyer
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6 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Recommended Texts - 5 Structural Bioinformatics Philip E. Bourne (Editor), Helge Weissig Beginning Perl for Bioinformatics James Tisdall Mastering Perl for Bioinformatics James D. Tisdall
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7 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” What is Bioinformatics?...
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8 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” ...What is Bioinformatics?... Computational Biology Bioinformatics Genomics Proteomics Functional genomics Structural bioinformatics
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9 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” ...What is Bioinformatics? Bioinformatics: collection and storage of biological information Computational biology: development of algorithms and statistical models to analyze biological data Bioinformatics/Computational Biology will be interchanged
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10 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Why is Bioinformatics Important? Applications areas include Medicine Pharmaceutical drug design Toxicology Molecular evolution Biosensors Biomaterials Biological computing models DNA computing
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11 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Why should I care? SmartMoney ranks Bioinformatics as #1 among next HotJobs Business Week 50 Masters of Innovation Jobs available, exciting research potential Important information waiting to be decoded!
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12 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” Why is bioinformatics hot? Supply/demand: few people adequately trained in both biology and computer science Genome sequencing, microarrays, etc lead to large amounts of data to be analyzed Leads to important discoveries Saves time and money
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13 “INTRODUCTION TO BIOINFORMATICS” “SPRING 2005” “Dr. N AYDIN” The Role of Computational Biology Source: GenBank 3D Structures Growth: Source: holdings.html GenBank BASEPAIR GROWTH
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