Peptides and proteins Part 2

Peptides and proteins Part 2 - Collagen – connective...

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Unformatted text preview: Collagen – connective tissue protein The repeating unit: (Gly-X-Pro) or (Gly-X-Hyp) Three individual helices are twisted around each other to form a stiff rod. Triple helical molecule ics called tropocollagen. The three strands are held together by hydrogen bonds. Cross-link in collagen Cross-link in elastin Silk fibroin The regularly repeating sequence: (Ser-Gly-Ala-Gly) n Antiparallel pleated sheet Structure of proteins- Tertiary – includes the three-dimensional arrangement of all atoms in the protein, including the atoms in the side chains and any prosthetic groups (ones other than amino acids)- In very large proteins, the folding of parts of the chain can occur independently of the foldinf of other parts. Such independently folded portions of proteins are referred to as DOMAINS- Forces stabilizing – hydrogen bonds between side chains, electrostatic attractions (salt, ionic bonds), hydrophobic interactions, Myoglobin...
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Peptides and proteins Part 2 - Collagen – connective...

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