KM_4160_Sept30-2019_8m.ppt - Vertebrate Physiology \u2022 Muscle Physiology(Ch 8 \u2022 Types \u2022 Skeletal muscle structure \u2022 Sliding filament Power stroke

KM_4160_Sept30-2019_8m.ppt - Vertebrate Physiology u2022...

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Muscle Physiology (Ch. 8) Types Skeletal muscle structure Sliding filament & Power stroke Excitation – contraction coupling Vertebrate Physiology Sept. 30, 2019 Paper topics due Today
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Extra Credit Opportunity for Exam 1: Attend one of the seminars listed below ( Monday Sep. 30 or Monday Oct. 7, 3:30pm in LSA 101 Auditorium ) Write a 1 page summary of the talk, things you learned, etc. Email it to me by Wed. of the same week (Oct. 2 or Oct. 9) Sept. 30: “Molecular Mechanisms Underlying Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia (HHT)” Stryder Meadows , Tulane University. Oct. 7: “Regulatory Mechanisms Underlying Apical Constriction During Tubular Organ Formation” Thao Le , LSU Department of Biological Sciences.
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Muscle Physiology Muscular system: Comprises largest group of tissues in the body Sartorius muscle (thigh) Smallest muscle in body? Stapedius muscle (~1mm long) (middle ear) Longest muscle in body?
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3 types of muscle Smooth Cardiac Skeletal
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Muscles Types Categorized according to control and structure : Control: Voluntary – skeletal Involuntary – cardiac, smooth Structure : Striated – skeletal, cardiac Unstriated – smooth
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Skeletal Muscle Structure Consists of muscle fibers lying parallel to one another, held together by connective tissue Single skeletal muscle cell is a muscle fiber multinucleated large, elongated, and cylindrically shaped fibers extend entire length of muscle muscle Muscle fiber
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Myofibril Muscle fibers are composed of myofibrils Each myofibril made of regular arrangement of thick and thin filaments: Thick filaments myosin protein Thin filaments actin protein myofibril
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Thick & Thin filaments of myofibrils (c) Cytoskeletal components of a myofibril M line Cross bridges I band Portion of myofibril H zone H zone A band I band Z line M line Z line Sarcomere Thick filament Thin filament A band Cross bridge Thin filament Thick filament
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Proteins of thick & thin filaments Thick filament Thin filament Tropomyosin Troponin Actin Myosin head Myosin tail
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Muscle structure summarized Whole muscle Muscle Fiber Myofibril Thick & Thin filaments Myosin & Actin Organ Cell Specialized intracellular structure Cytoskeletal elements Proteins Levels of organization
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Sarcomere: functional unit of skeletal muscle Sarcomere Smallest component that can perform the main function of that organ myofibril Z line Z line
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