Sinh lí Thận.pptx - GS TS PHAM ĐINH LƯU SINH LY THÂN LOGO www.themegallery.com THÂN Thận là c� quan sinh mạng Có nhiệm vụ tạo

Sinh lí Thận.pptx - GS TS PHAM ĐINH LƯU SINH LY...

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LOGO GS TS PH M ĐINH L U A Ư SINH LY TH N Â GS TS PH M ĐINH L U A Ư SINH LY TH N Â
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TH N Â Th n là c quan sinh m ng ơ Có nhi m v t o n c ti u đ làm 2 ch c ụ ạ ướ năng : Đào th i cái s n ph m chuy n hoá C0 2, H + , NH 3, Urê…. Gi h ng đ nh n i môi
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1. S L C V C U TRUC Ơ ƯƠ Ê Â Th n đ c c u t o b i nh ng đ n v th n: ượ ơ nephron Nephron: đ n v c u trúc, ch c năng t o n c ơ ướ ti u thành ph m M i th n có: 1.200.000 nephron M i nephron g m: c u th n và ng th n ng th n có 3 đo n : ng g n (Proximal tubule) Quai Henle (Loop of Henle) ng xa (Distal tubule). ng xa đ vào ng góp (collecting duct)
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1. S L C V C U TRUC Ơ ƯƠ Ê Â kho ng 8 ng xa đ vào ng góp nh ng góp nh đ vào ng góp trung bình ng góp trung bình đ vào ng góp l n, có kho ng 250 ng góp l n đ vào b th n M i ng góp l n t p h p kho ng 4000 ỗ ố nephron.
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Nephron C u t o c a nephron Ti u c u th n ng l n g n ượ ng l n ượ xa Quai henle B th n V th n T y th n Đo n m ng Đo n dày Nang Bowman Ph c h p c n c u th n ng góp ng góp v ng góp t y 80% nephron vung v Ơ 20% nephron vung c n t y Ơ
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C u t o c a th n Th n Ni u qu n Bàng quang Ni u đ o Đ ng m ch th n Ni u qu n Đài th n bé Đài th n l n Nephron V th n T y th n B th n Bao th n Gi i ph u H ti t ni u ê
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1. S L C V C U TRUC Ơ ƯƠ Ê Â Toàn b nephron và ng góp đ c bao b ng t bào ượ ế bi u mô (epithelial cells) M ch máu th n: xu t phát t ĐM ch b ng u ĐM gian thuỳ ĐM vòng cung ĐM gian ti u thuỳ Ti u đ ng m ch vào c u th n Ti u đ ng m ch vào c u th n (afferent arteriole) chia thành 50 quai mao m ch trong c u th n, r i t p trung l i thành ti u đ ng m ch ra (efferent arteriole) l i chia thành m ng mao m ch th 2 đ nuôi nephron, h này g i là đ ng m ch gánh. Riêng 20 % nephron c n tu , ti u đ ng m ch ra t o thành quai mao m ch th ng vasarecta ch y song song v i các quai Henle th c sâu vào trong tu th n
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1. S L C V C U TRUC Ơ ƯƠ Ê Â Mô th n Mao m ch ch c năng ư (trong c u th n) â Mao m ch dinh d ng ươ (mao m ch quanh ng) ô Ti u ĐM vao ê Ti u ĐM ra ê TK th n la TK giao c m ơ a
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2. S L C C U TH N Ư O
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