Chapter_10 .ppt - Chapter 10 Antiviral Agents Copyright \u00a9 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Viruses That Respond to Antiviral

Chapter_10 .ppt - Chapter 10 Antiviral Agents Copyright...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 10: Antiviral AgentsChapter 10: Antiviral Agents
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Copyright © 2017 Wolters Kluwer • All Rights ReservedViruses That Respond to Antiviral TherapyViruses That Respond to Antiviral TherapyInfluenza A and some respiratory virusesHerpes virusesCytomegalovirus (CMV)Human immunodeficiency virus (HIV) that causes acquired-immune deficiency syndrome (AIDS)Hepatitis B and CSome viruses that cause warts and certain eye infections
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Copyright © 2017 Wolters Kluwer • All Rights ReservedCharacteristics of Common VirusesCharacteristics of Common VirusesA virus cannot replicate on its ownIt must attach to and enter a host cellIt then uses the host cell’s energy to synthesize protein, DNA, and RNA.Viruses are difficult to kill because they live inside our cellsAny drug that kills a virus may also kill our cells
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Copyright © 2017 Wolters Kluwer • All Rights ReservedStages of Virus ReplicationStages of Virus Replication
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Copyright © 2017 Wolters Kluwer • All Rights ReservedCharacteristics of Antiviral DrugsCharacteristics of Antiviral DrugsAble to enter the cells infected with virusInterfere with viral nucleic acid synthesis and/or regulationSome agents interfere with ability of virus to bind to cellsSome agents stimulate the body's immune systemKNOW: Acyclovir (Zovirax) and Zidovudine (AZT)**Note most antiviral –VIR endings**
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Copyright © 2017 Wolters Kluwer • All Rights ReservedCommon Respiratory VirusesCommon Respiratory VirusesInfluenza AInfluenza BRespiratory Syncytial Virus (RSV)
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