Chapter_51.ppt - Chapter 51 Diuretic Agents Copyright \u00a9 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Classes of Diuretics \u2022 Thiazide and

Chapter_51.ppt - Chapter 51 Diuretic Agents Copyright...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 51: Diuretic AgentsChapter 51: Diuretic Agents
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Copyright © 2017 Wolters Kluwer • All Rights ReservedClasses of DiureticsClasses of DiureticsThiazide and Thiazide-like DiureticsLoop DiureticsCarbonic Anhydrase InhibitorsPotassium-Sparing DiureticsOsmotic Diuretics
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Copyright © 2017 Wolters Kluwer • All Rights ReservedFunction of Diuretic AgentsFunction of Diuretic AgentsIncrease the amount of urine produced by the kidneysIncrease sodium excretion
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Copyright © 2017 Wolters Kluwer • All Rights ReservedIndications for Diuretic UseIndications for Diuretic UseEdema associated with congestive heart failureAcute pulmonary edemaLiver disease (including cirrhosis)Renal diseaseHypertensionConditions that cause hyperkalemia
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Copyright © 2017 Wolters Kluwer • All Rights ReservedSites of Action of Diuretics Sites of Action of Diuretics
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Copyright © 2017 Wolters Kluwer • All Rights ReservedUse of Diuretic Agents Across the LifespanUse of Diuretic Agents Across the Lifespan
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Copyright © 2017 Wolters Kluwer • All Rights ReservedThiazide and Thiazide-Like DiureticsThiazide and Thiazide-Like DiureticsKNOW: Hydrochlorothiazide (HydroDIURIL, HCTZ) Chlorothiazide (Diuril)Bendroflumethiazide (Naturetin)Benzthiazide (Exna)Hydroflumethiazide (Diucardin)Methyclothiazide (Aquatensen)Polythiazide (Renese)Trichlormethiazide (Diurese) **Note –THIAZIDE endings**
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Copyright © 2017 Wolters Kluwer • All Rights ReservedThiazide and Thiazide-Like Diuretics (cont.)Thiazide and Thiazide-Like Diuretics (cont.)ActionsAction is to block the chloride pumpKeeps chloride and the sodium in the tubule to be excreted in the urine, thus preventing the reabsorption of both in the vascular system
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