Lect_2_Notes - serves as a template for protein synthesis...

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Bio 1A Lecture 2 January 25, 2008 Professor Schlissel Storage, retrieval, and transmission of information 1) DNA is the genetic material—Avery, McCarty, McLeod experiment. Bacterial transfomation. Bacteriophage. Hershey & Chase experiment. 2) Watson and Crick’s structure of DNA 3) Nucleic acids—nucleotides, nucleosides, bases, RNA vs. DNA, polymers, phosphoester bonds, base-pairing, nucleic acid hybridization 4) Where is DNA within cells— eukaryotes have DNA in the nucleus and in mitochondria 5) Each cell contains all of the information necessary to specify a complete animal. Cloning: generating a new individual starting with a single cell 6) The Central Dogma: DNA serves as a template for RNA synthesis which
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Unformatted text preview: serves as a template for protein synthesis. Transcription. Translation. 7) The relatedness of organisms can be discerned by comparing their DNA sequences. Mitochondrial DNA is particularly useful in this regard. 8) Models for DNA replication. The Messelsohn-Stahl experiment. Semi-conservative replication. DNA replication proceeds in a 5’ to 3’ direction. 9) The Gene—fundamental physical and functional unit of heredity; one gene codes for one polypeptide (or trait) (an oversimplification) 10) Four different categories of DNA in cells—mRNA, rRNA, tRNA, and small RNAs. 11) Transcription is the process in which an RNA copy is made from a DNA template. Differences between prokaryotic and eukaryotic mRNA structure....
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