06 Energetics and Catabolism.pptx - Bacterial Metabolism • Metabolism – Sum of all the chemical processes that occur within a cell • Anabolism

06 Energetics and Catabolism.pptx - Bacterial Metabolism...

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Bacterial Metabolism Metabolism Sum of all the chemical processes that occur within a cell Anabolism : Synthesis of more complex compounds and use of energy Catabolism : Break down a substrate and harness energy
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Overview of microbial metabolism
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Bacterial Metabolism Autotrophs: synthesize their own complex metabolites from inorganic sources Photosynthetic bacteria Chemoautotrophic bacteria Heterotrophs: acquire complex nutrients from external sources Parasites Saprophytes
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Bacterial Patterns of Metabolism
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Bioenergetics The tendency in nature is toward higher disorder ( entropy ) To maintain order, energy must be applied to a system The cell is the organic world’s hedge against entropy Homeostasis, growth and reproduction requires the addition of an extraordinary amount of energy The study of how cells acquire, convert and expend energy is called bioenergetics
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Bioenergetics Biological systems utilize a variety of organic substrates as fuel Carbohydrates Fats Proteins This fuel is used generate a secondary stable energy source: adenosine triphosphate (ATP)
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ATP
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ATP Water soluble, fairly stable Very abundant in cells (precursor of RNA synthesis) Standard free energy (25 o C, pH 7) of hydrolysis of γ -phosphate : -7.3 kcal/mole In cytoplasm, actual free energy yield may be as high as -12 kcal/mol
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Bioenergetics From the overview diagram it is obvious that the generation of ATP is the last step in a very complex series of energy conversion reactions Many of these steps involve the chemical process of oxidation (loss of 2 electrons
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  • Spring '14
  • LawrenceR.Aaronson

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