Topic2.pdf - Topic 2 Amino Acids and the Peptide Bond Readings p 55-56 74-75 After completing this topic you should be able to 1 Describe the general

Topic2.pdf - Topic 2 Amino Acids and the Peptide Bond...

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Page 1 of 2 Topic 2: Amino Acids and the Peptide Bond Readings: p. 55-56, 74-75 After completing this topic, you should be able to: 1. Describe the general structure of amino acids and different classes of amino acids. 2. Describe how amino acids are linked to form proteins. 3. Calculate the net charge on an amino acid side chain given its p K a . More properly known as α -amino acids, their general structure is at right: Nineteen of the twenty amino acids have the same arrangement around the central α -carbon (blue): a. the α -amino group, b. the α - carboxyl group, c. a hydrogen, and d. an R group (called the "side chain") which differs for each amino acid. Recall that when 4 different substituents are bonded to a carbon atom, stereoisomers are possible. Therefore, amino acids are designated as D- and L-amino acids. All but one of the amino acids have D- and L- isomers; only the L- forms are incorporated into proteins. An important property of amino acids is ionization of weakly acidic or basic groups present on the molecule. The ionization of a group changes as the hydrogen ion
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  • Spring '12
  • Deroo
  • Notes, biochem

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