Lecture7.pdf - • • • • • • • • • • • SNPs are(single nucleotide polymorphism it’s a single base change a single base pair is

Lecture7.pdf - • • • • • • • • • • •...

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SNPs are (single nucleotide polymorphism) it’s a single base change, a single base pair is different There is a change in the DNA sequence its still a mutation whether or not it effects anything CNV -copy number variation (different number of copies of genes than someone else) Insertion sequences code for transposase which allows a gene to move around from one part of the genome to another Some genes can cut themselves out and insert themselves to another place in the genome We have retroviruses In out genome that makes them stuck in the genome due to a mutation millions of years ago Evolution only cares about mutation that give life to gametes (sperm or egg cells) SNPs come from replication errors Each of the nitrogenous bases has an alternative tautamoric form where it can bond with the base its not supposed to. This is
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Unformatted text preview: possible but cannot sustain DNA and life • There are certain bases and certain chemicals that will look just like a nitrogenous base but it switches its tatmeric form an example is (5-bromouracil) • African population have more variability, maybe because african populations are older and the other population are decenedants of african populations (african populations have more SNP's, these SNPs come from replication errors) SNPs • Snps come from replication errors • The nitrogenous bases are stable in a particular tautomeric form • Each of the bases has its own tautomeric form, life is only possible in the most stable form where A bond with T and G bonds with C • But sometimes bases can switch their tautomeric form and call the wrong base (they still call the same type of base (purine/ pyrimadine)...
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  • Fall '13
  • TomHaffie

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