09-20-06 (8) Protein - Polypeptides Proteins Proteins...

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Polypeptides & Proteins September 20, 2006
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Proteins Proteios (Greek) = first place Account for more than 50% of dry mass
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Proteins Have many structures and functions The diversity in function is a result of the diversity in structure Diversity in structure has its basis in the sequence of joined monomers
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Overview of Protein Function
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Proteins as Enzymes Substrate (sucrose) Enzyme (sucrase) Glucose OH H O H 2 O Fructose 2 *Purpose of sucrase is to hydrate sucrose
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Polypeptides vs. Proteins Polypeptide -Polymers of amino acids (monomers) Protein -one or more polypeptides folded and coiled into a specific functional conformation
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Amino Acids Monomers of polypeptides & proteins Organic molecules possessing both a carboxyl group and an amino group
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Amino Acids N C C O OH H H R H α carbon Carboxyl group Amino group
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Amino Acids 20 different amino acids that cells use to build their proteins Differ only in their R group Differ in their properties due to differing R groups
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Amino Acids Categorize amino acids based on properties of side chains ( R groups): Polar & Uncharged Polar & Charged Nonpolar
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Polar & Uncharged Amino Acids
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Polar & Charged Amino Acids
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Nonpolar Amino Acids
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Nonpolar** Amino Acids
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Polypeptides Amino acid polymers Amino acids joined by a peptide bond
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Peptide bond formation DESMOSOMES DESMOSOMES DESMOSOMES OH CH 2 C N H
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