cell injury(1).pdf - PATHOPHYSIOLOGY CELL INJURY CELL DEATH Overview of Cellular Injury • Cells actively control the composition of their immediate

cell injury(1).pdf - PATHOPHYSIOLOGY CELL INJURY CELL DEATH...

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PATHOPHYSIOLOGY CELL INJURY & CELL DEATH
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Cells actively control the composition of their immediate environment and intracellular surrounding within a narrow range of physiological parameters (“ homeostasis ”) Under physiological stresses or pathological stimuli (“ injury” ), cells can undergo adaptation to achieve a new steady state that would be compatible with their viability in the new environment. Cellular injury may be a reversible process, in which case the cells can recover their normal function, or it may be irreversible and lead to cell death and necrosis If the injury is too severe (“ irreversible injury ”), the affected cells die. Overview of Cellular Injury
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Overview of Cellular Injury
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Reversible and Irreversible Cell Injury
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