L&S Final Review - SCHEDULES 1 No accepted med use in...

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SCHEDULES 1 2 3 4 No accepted med use in the US High potential for abuse LSD Most opiods Opiods in certain combos DMT Opium Poppy anabolic steroids All benzodiazepines (Valium) heroin Morphine Tylenol sedative hypnotics methaqualone (Quaalude) Fentanyl lysergic acid amide (precursor to LSD) psychedelics/hallucinogens Methadone GHB - clinical use only THC Cocaine cannabis Coca Leaves 5 GHB Methamphetamine (speed) Barbituates Codeine (cough syrup) NOT SCHEDULED: tobacco, alcohol, salvinorin A SCHEDULE CHANGE: Methaqualone Quualude (benxodiazepines) from Schedule 4 --> Schedule 1 NOT SCHEDULED: absinthe, but is illegal in US because of 1920s law NOT SCHEDULED: Khat, though component cathinon is listed SCHEDULE NOTE: DMT is Schedule 1, but Supreme Court ruled that some religious sects could use it SCHEDULE NOTE: LSD is also Schedule 1 internationally SCHEDULE NOTE: GHB is Schedule 1, but Schedule 3 when clinical research SCHEDULE NOTE: Merinol is pharmaceutical version of Marijuana (GHB)
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NEUROTRANSMITTERS GABA Glutamate Dopamine Serotonin (5HT) 1st most abundant2nd most abundant Inhibitory Excitatory can't cross blood-brain barrier raphe nuclei of brain Adenosine Endorphins Norepinephrine Cannabinoids endogenous morphine 3rd most abundant Inhibitory retrograde signaling i vasodilation (constricts blood vessels) effects in the cardiovascular system Acetylcholine Andandamide endogenous neurotransmitter activates cannabinoid receptor in cacao
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nstem in synapse
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Solanaceous Plants Cannabis Potatos, tomatoes poisonous leaves, 5 petals Duboisia hopwoodii
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Nicotine Tropane alkalo Cocaine Amphetamine Cathinone Thujone Salvinorin A Caffeine Alcohol THC Opium Coca LSD - lysergic acid diethylamide psilocybin & psilocin Plant Nicotiana tabacum Atropa belladonna (coca) Catha edulis (K Artemisia absi Salvia Divinorum Coffea arabica (coffee) Camelia sinensis (tea) Theobroma cacao (chocolate) Saccharomyces cerevisiae Cannabis sativa Cannabis indica Others? (marijuana) Papaver somn Ephedra sinica Erythroxylum c Ipomoea violecea (morning glory) Psilocybe cubensis (psychedelic mushroom) Receptor agonist--nicotinic acetylch antagonist--at blocks reup leaky reuptake transmitters affects dopamine, norepinephri antagonist--GA agonist--kabba-op antagonist--ad inhibits glutamate inhibits adenosine increase action of GABA (not true agonist)
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