Nucleophilic Aromatic Substitution Experiment Worksheet Spring 2019.pdf - Nucleophilic Aromatic Substitution Experiment Name TA Score/15 In preparation

Nucleophilic Aromatic Substitution Experiment Worksheet Spring 2019.pdf

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Nucleophilic Aromatic Substitution Experiment Name: ______________________ Score: ____/15 TA: ________________________ In preparation for this worksheet, review the 12 principles of green chemistry. One website where these can be found is . 1. What are three areas in which the reaction you performed adhered to the principles of green chemistry? Explain your reasoning. 2. What are two areas in which the reaction you performed did not adhere to the principles of green chemistry? 3. In your own words, what does systems thinking mean? 4. What evidence do you have that TPGS-750M increases the reaction rate? How does TPGS-750M act to
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Unformatted text preview: increase the reaction rate? 5. Did you correctly predict which 2-halo-5-nitropyridine would react the fastest? Discuss which substrate had the faster reaction rate and provide a plausible explanation, including which step in the mechanism is the rate limiting step. Which is more important in determining the rate of the reaction, the halogen’s size or electronegativity? 6. What was the yield for your isolated product? Draw the structure of your final product and state (and analyze) the evidence you have that you correctly isolated this product. As part of this discussion, you should print off and annotate your IR, as well as the spectra found on Gauchospace....
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