Chapter 30 Assignment Patho 2019.docx - Laxatives are used primarily to treat constipation There are many different name used interchangeably for

Chapter 30 Assignment Patho 2019.docx - Laxatives are used...

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Laxatives are used primarily to treat constipation. There are many different name used interchangeably for example cathartics, purgatives or evacuants. Laxatives can act by different mechanisms but there is considerable overlap between the different groups. So the mechanism of action is an hydrophilic element that draws water into the stools. This makes the stool easier to transition to the colon so the bowel can have a good movement. There are many different pharmacology class of drugs that are laxatives. Bulk-forming laxatives retain fluid in the stool and increase stool weight and consistency, example will be psyllium and dietary fiber. Osmotic agents contain substances that are poorly absorbable and draw water into the lumen of the bowel. The most commonly used will be milk of magnesia, lactulose, sorbitol, and polyethylene glycol. Surface active agents like docusate lower surface tension which leads to water and fats penetrating into the stool. Finally, lubricants like mineral oil aid in the passage of stools.
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