BB 2019 Fall Chapter 10.ppt - CHAPTER 10 MUSCLE TISSUE Muscle Function •Generate movement •Generate force •Role in Maintaining

BB 2019 Fall Chapter 10.ppt - CHAPTER 10 MUSCLE TISSUE...

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Muscle Function Generate movement Generate force Role in Maintaining Temperature (skeletal)
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Muscle Types Skeletal muscle Voluntary Striated Control movement of the body Cardiac muscle Involuntary Striated Found in the heart Moves blood through circulatory system Smooth muscle Involuntary Not striated Muscle found in internal organs like stomach, urinary bladder, blood vessels Moves material through the body
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Figure 10.2 From top, LM × 1600, LM × 1600, LM × 1600. (Micrographs provided by the Regents of University of Michigan Medical School © 2012) The Three Types of Muscle Tissue The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle (c) cardiac muscle.
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Skeletal Muscle Skeletal muscle structure Skeletal muscles attached to bones - tendons Tendons form sheaths that extend around and into skeletal muscle Connective tissue divides muscle into columns called fascicles Muscle fascicles = bundle of muscle fibers
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Skeletal Muscle Skeletal muscle cells or muscle fibers Muscle cells are multinucleate and striated Plasma membrane of muscle cell = sarcolemma Cytoplasm = sarcoplasm Modified endoplasmic reticulum = sarcoplasmic reticulum Ca ++ sequestered at terminal cisternae T – tubules – membranous continuation of sarcolemma, closely associated with terminal cisternae
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Skeletal Muscle Each muscle fiber is packed with myofibrils, Myofibrils are packed with myofilaments, thick and thin protein filaments that give rise to “striations” A myofibril has a repeating pattern of light and dark bands One repeat = sarcomere
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Figure 10.5 The Sarcomere The sarcomere, the region from one Z-line to the next Z-line, is the functional unit of a skeletal muscle fiber.
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Skeletal Muscle Sarcomere – contractile unit of skeletal muscle consisting of components between two Z discs A band – dark band, contains thick filaments (mostly myosin) H band – light area at the center of A band, here actin and myosin do not overlap I band – light band that contains thin filaments (mostly actin) Z line/disc – at the center of the I band where actins attach M line – structural proteins that anchor myosin during contraction
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Figure 10.7 The T-tubule Narrow T-tubules conduct electrical impulses. The SR regulates intracellular Ca ++ levels. Two terminal cisternae (where enlarged SR connects to the T-tubule) and one T- tubule comprise a triad—a “threesome” of membranes, with those of SR on two sides and the T-tubule sandwiched between them.
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Skeletal Muscle The neuromuscular junction Single synaptic ending of somatic motor neuron that innervates each muscle fiber Area on the sarcolemma where the NMJ = motor end plate Each motor neuron branches to innervate a variable number of muscle fibers Diagram from Fox
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Figure 10.6 Motor End-Plate and Innervation At the NMJ, the axon terminal releases ACh.
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  • Fall '16
  • Dusti Sloan

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