MCB102 Midterm 1 Questions - 1 Ligand 2 Prosthetic group 3...

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1. Ligand 2. Prosthetic group 3. Induced fit – 4. Allostery – 5. Cooperativity – 6. Kd = ? Kd for multiple interdependent ligand binding events = ? 7. The value of [L] when theta = 0.5 is the _____ (or 1/___) 8. Fe2+ in hemoglobin and myogoblin is an example of a ___________ 9. Draw an edge view of the Fe2+ coordinating in the heme molecule. 10. How does O2 bind better than CO? 11. What conformation of hemoglobin has low O2 affinity?
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Unformatted text preview: 12. Which conformation of hemoglobin forms salt bridges? What function do the salt bridges serve? 13. What does the hill coefficient indicate? 14. Slope must be ______ than the total number of ligands bound. 15. Sequential model – 16. Explain why on the molecular level why sickle-cell anemia is bad 17. Write Michaelis Menten Equation...
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  • Spring '08
  • Staff
  • Hemoglobin, Michaelis Menten equation, hemoglobin forms salt, multiple interdependent ligand

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