Unformatted text preview: such as n, may play a role in hypermutation of immunoglobulin genes.
In Prokaryotes DNA pol III conducts both leading and
lagging strand synthesis
First: DNA pol a associate with primase to synthesize a
short RNA-DNA hybrid primer
Second: 'Polymerase switch' occurs where DNA pol a is
swapped for & or 8 depending on the strand
. DNA pol & is used for the elongation of the leading
. DNA pol 8 is used for the elongation of the lagging
VI) End of Chromosome Replication Problem...
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- Fall '13