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bis103win07midterm2key2

bis103win07midterm2key2 - BIS103-002 MIDTERM 2 Winter 2007...

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BIS103-002 MIDTERM 2 Winter 2007 Instructor: Callis Name_________________________________________________ February 27, 2007 LAST NAME FIRST NAME 1 Student ID # _______________________________________ Check the appropriate boxes below Open Campus Enrolled Completing Incomplete Not enrolled, doing this for fun. Note: There are 6 questions and a total of 10 numbered pages counting the cover sheet. A blank sheet is included in the back for scratch paper and to cover your exam. Do not use this paper for your answers. If you need more room use the back of the numbered pages. Partial credit will be given. WRITE YOUR NAME ON THE TOP OF EACH PAGE. Question Value Score 1 22 2 16 3 14 4 16 5 12 6 20 TOTAL 100 T= 298º K R= 8.315 J x mol -1 x K -1 Faraday's constant (F) is 96.5kJ x volt -1 x mol -1 Δ G o ' for the reaction ADP + P i ATP + H 2 O = + 30.5 kJ x mole -1 Δ G o ' = - n F Δ E o ' Δ G = Δ G o ' + RT ln [products/reactants] for Aox + 1 e- Ared E = E o ' - RT ln A red nF A ox I, ______________________________, authorize the University to distribute publicly this graded exam ( e.g. , handed out in class, or left in a bin for me to pick up). Signature ________________________________________ Date _____________________
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BIS103-002 MIDTERM 2 Winter 2007 Instructor: Callis Name_________________________________________________ February 27, 2007 LAST NAME FIRST NAME 2 1. (a). (10 pts). If ATP, AMP and NADH were allosteric regulators of the enzymes that catalyze the reactions listed below, based on your knowledge of the pathway in which these reactions operate, predict the mostly likely effect [ writing either an “A” for activation or a “I” for inhibition] that each regulator (NADH, ATP, and AMP) might be expected to exhibit on the enzyme activity that catalyzes the reaction. NADH ATP AMP 1. Citrate + CoA + ATP acetyl CoA + ADP + OAA A A I 2. Fructose-1,6 bisP + H 2 O Fructose-6-P + HPO 4 3- A A I 3. Acetyl CoA + HCO 3 - + ATP Malonyl CoA + ADP + HPO 4 3- C O S CoA C C H H O O - Malonyl CoA A A I 1(b). (12 pts, 2 pts each). Rat liver is able to metabolize glucose by both the aerobic glycolytic pathway and the pentose phosphate pathway. For each statement below, write in the blank space in front of the line, G if the statement and/or property is true of glycolysis only , write the letter P if true of pentose phosphate pathway only , write “ G + P ” if true of both pathways , or write N for neither, if not true of either pathway . You may use the letters more than once. __ G + P ____ Pathway (s) begins with a physiologically irreversible reaction ______ P ____ Ribose-5-P is synthesized ______ G _____ NAD + is consumed __ G + P ____ Phosphate esters are involved ______ P _____ CO 2 is liberated __ G + P ____ Pathway (s) serve multiple purposes in cell
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BIS103-002 MIDTERM 2 Winter 2007 Instructor: Callis Name_________________________________________________ February 27, 2007 LAST NAME FIRST NAME 3 2. (16 pts) (a). (6 pts total, 2 pts each). Acetyl CoA in mammals is the biosynthetic precursor for other biomolecules. Write the names below on the lines provided three different classes of molecules for which acetyl CoA serves as the net biosynthetic precursor. Name a compound that has a biological role other than serving as precursor for another molecule.
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