Lecture 9 - Click to edit Master subtitle style Lecture 9...

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Click to edit Master subtitle style 6/22/09 Lecture 9
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6/22/09 Learning Objectives: To define immunity and the mechanisms involved in immunity To describe the two immune responses; innate and adaptive immunity To acquire knowledge of the various immune effector cells To describe the two branches of
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6/22/09 Learning Outcomes: At the end of the lecture, students will be able to: describe immunity and the mechanisms that involved in immune responses describe the various cells and some of mechanisms involved in adaptive and innate immunity explain the mechanisms behind humoral and cell-mediated immune response of
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6/22/09 Are you aware that we are constantly exposed to various antigens at all
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6/22/09 The Defense Mechanism Defining Immunity Self and non-self recognition Triggered by antigens Antigen: Foreign molecules/particles recognized as non-self Classes of antigens Two types of immunity:
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6/22/09 Innate Immunity First line of defense against infection with any invading microorganisms Components are present before onset of infection Rapid response (in hours) Response to repeat antigenic challenge remain constant Uniform in all members of a species
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6/22/09 Adaptive Immunity Develops following primary exposure to a pathogen (acquired) or recognized antigenic challenge to the organism Highly specific to a particular pathogen Recognize a wide repertoire of foreign substances Not same in all members of a species
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6/22/09 Three Lines of Defense Physical barriers: Skin, mucosal surfaces lining the respiratory, gastrointestinal and urogenital tracts Innate Immunity: Phagocytes (neutrophils, macrophages), NK cells, dendritic cells Get rid of the antigens before infection becomes established
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6/22/09 The Cells and Molecules Circulate in the blood and lymph Some found at the tissues Release chemicals upon being activated; cytokines Can be found in the innate and adaptive immune response Cytokines – important chemical secretions that govern the immune response
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6/22/09
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6/22/09 The Cells and Molecules Involved
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This note was uploaded on 06/21/2009 for the course BIO 150 taught by Professor Kore during the Spring '08 term at Abraham Baldwin Agricultural College.

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Lecture 9 - Click to edit Master subtitle style Lecture 9...

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