Chapter 11 - 1 Cell communication Membrane transport...

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Unformatted text preview: 1 Cell communication Membrane transport cytoskeleton Cell Membranes 1. Plasma membrane defines a cell 2. Separates inside from outside 3. Resistant to stress 4. Allows information flow Internal membranes - compartmentalize the cell Allows •specialized chemistry (acid) •specialized functions 2 1. Lipids Distinct physical properties dictate formation & behavior of membrane bilayer Two interrelated concepts: 2. Cell membranes – “THE” ultimate bilayer Utilizes properties of lipid for flexibility, resistance and motility PROTEIN components yield cell function – bypass “problems” associated with lipids Membranes Consist of lipid bilayer with embedded proteins proteins can be and often are glycosylated on external face proteins provide function Very thin ~ 50 atoms across, ~ 50 nm can not see with light microscope BUT it is property of lipids that allow formation of the bilayer. 3 Saturated = no double bonds chain is straight Unsaturated - C=C - double bonds creates kinks in chain Lipid bilayer- a natural structure based on chemical properties of lipid Lipids consist of fatty acid chains …. attached to glycerol = FAT (oil) Does not mix with water . But phospholipids are amphipathic molecules: • form majority of membrane lipid • critical to formation of lipid BILAYER . “water loving” - presence of hydrophillic groups- polar and ionic groups can form H- bonds with water -- dissolve in water “water-hating” -- non-polar and uncharged atoms can not interact with water water becomes ordered, therefore less favorable 4 Remember: “Like dissolves like?” hydrophillic hydrophobic Water is more ‘ordered’ around hydrophobic molecules - less entropy. 5 Whole molecule does not like...
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This note was uploaded on 04/02/2008 for the course BIO 2600 taught by Professor Vanburkem during the Winter '08 term at Wayne State University.

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Chapter 11 - 1 Cell communication Membrane transport...

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