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NURS 761PharmacotherapeuticsAutonomic Nervous System DrugsSympathetic & ParasympatheticAgonists & Antagonists – Part 2 (Adrenergics)Fall 2018Faculty: Dr. Cheryl OetjenDr. Carol Urban
Learning Objectives1.Identify the action and pharmacologic action of adrenergic agonists and antagonists.2.Describe the clinical indications for adrenergic agonists and antagonists, including selective drugs.3.Identify patients who are at increased risk for negative outcomes of pharmacotherapeutics with adrenergic agonist and antagonist drugs.4.Develop a teaching plan to ensure optimal patient outcomes.
Drugs to Know•Adrenergic Agonists:•epinephrine, pseudoephedrine (non-selective)•phenylephrine, midodrine (alpha-1)•albuterol, terbutaline (beta-2)•clonidine, methyldopa (alpha-2 agonists)•Adrenergic Antagonists•prazosin, tamsulosin, silodosin, phentolamine (alpha-1 blockers)•“-lol” (selective and nonselective beta blockers, some are also alpha-1 blockers)
Adrenergic Agonists•Sympathomimetic, include naturally occurring and synthetic catecholamines•Three main effects: vasoconstriction, cardiac stimulation, bronchodilation•Additional effects: nasal and ophthalmic decongestants