PhysioEx Exercise 4 Activity 1.pdf - PhysioEx Exercise 4 Activity 1 PhysioEx Lab Report Exercise 4 Endocrine System Physiology Activity 1 Metabolism and

PhysioEx Exercise 4 Activity 1.pdf - PhysioEx Exercise 4...

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1/16/2020 PhysioEx Exercise 4 Activity 1 1/12 PhysioEx Lab Report Exercise 4: Endocrine System Physiology Activity 1: Metabolism and Thyroid Hormone Name: Anne Doan Date: 16 January 2020 Session ID: session-635c4247-78f6-1bb7-a883-57e959694608 Pre-lab Quiz Results You scored 83% by answering 5 out of 6 questions correctly. Experiment Results Predict Questions Which of the following statements about metabolism is false ? You correctly answered: All of the energy from metabolism is ultimately stored in the chemical bonds of ATP. 1 Thyroxine is You correctly answered: the most important hormone for maintaining the metabolic rate and body temperature. 2 Thyroid-stimulating hormone (TSH) is You correctly answered: produced in the pituitary gland. 3 An injection of TSH to an otherwise normal animal will cause which of the following? Your answer: hypothyroidism. Correct answer: goiter development. 4 Thyrotropin-releasing hormone (TRH) is You correctly answered: secreted by the hypothalamus. 5 Which of the following statements is true? You correctly answered: The hypothalamus primarily secretes tropic hormones that stimulate the secretion of other hormones. 6 Predict Question 1: Make a prediction about the basal metabolic rate (BMR) of the remaining rats compared with the BMR of the normal rat you just measured. 1
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1/16/2020 PhysioEx Exercise 4 Activity 1 2/12 Stop & Think Questions Your answer: The hypophysectomized (Hypox) rat's BMR will be higher than the normal rat's BMR. Predict Question 2: What do you think will happen after you inject thyroxine into the three rats? Your answer: The thyroidectomized rat will become hyperthyroidic and develop a goiter. 2 Predict Question 3: What do you think will happen after you inject TSH into the three rats? Your answer: The normal rat will become hyperthyroidic and develop a goiter. 3 Predict Question 4: Propylthiouracil (PTU) is a drug that inhibits the production of thyroxine by blocking the attachment of iodine to tyrosine residues in the follicle cells of the thyroid gland (iodinated tyrosines are linked together to form thyroxine). What do you think will happen after you inject PTU into the three rats? Your answer: The normal rat will become hypothyroidic and develop a goiter. 4 Calculate the oxygen consumption per hour for this rat using the following equation. ml O consumed/1 minute x 60 minutes/hour = ml O /hour Enter the oxygen consumption per hour. You answered: 426 ml O /hr. 1 2 2 2 Now that you have calculated the oxygen consumption per hour for this rat, you can calculate the metabolic rate per kilogram of body weight with the following equation (note that you need to convert the weight data from grams to kilograms to use this equation).
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