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AntidepressantsPossible Indications: Depression, Eating disorder, Pain disorder, Enuresis, OCD, GAD, PTSD, Paraphilias, PMS, Smoking cessation. Therapeutic effects: Mood: Reduce sadness, irritability, and anhedonia. Thoughts: Reduce hopelessness, pessimism, guilt, and suicidal thoughts, improve concentration and memory.Behavior: Improve diminish libido; reduce somatic complaints; improve energy and appetiteSleep: Improve sleep disturbance (insomnia, early morning awakening, hypersomnia)Onset: All antidepressant may take as long as 6 weeks to achieve therapeutic effect and may take longer for maximum benefit.Monoamine Oxidase Inhibitors (MAOI)GenericBrandDoseHalf-lifeTranylcypromineParnate®10 – 60 mg/dunknownPhenelzineNardil®7.5 – 90 mg/dunknownIsocarboxazidMarplan®10 – 60 mg/dunknown* Selegiline TransdermalSystem* Emsam®6 mg – 9 mg/24 hr16 – 69 hoursTyramineis an amino acid released from proteins during aging, fermenting, pickling, smoking, and spoiling. In the body, tyramine triggers the release of norepinephrine from adrenergic nerve endings and is then deactivated by monoamine oxidase (MAO) in the liver and intestine. However, in a patient taking a MAO inhibitor, tyramine levelsmay increase and cause large amounts of norepinephrine to be released, which could lead to a hypertensive reaction and intracranial bleed. Aged CheesesBlue Gouda RomanoCamembert Parmesan StiltonCheddar Provolone SwissAlcoholic BeveragesBeer Liqueurs SherryCognac Red WineFishCaviar Fermented, aged SmokedShrimp paste cured or dried Pickled FruitsBananas RaisinsFig PrunesMeatsBeef or chicken liver Smoked and processed meatsCorned beef (such as bologna, pepperoni, salami)VegetablesAvocados Fermented bean curd SauerkrautChinese pea pods Olives PicklesFava beans Flat Italian Beans Soybean pasteOther SourcesBeverages containing caffeine Monosodium Glutamate