MedicationNameFluconazole (Diflucan)Trade NameDiflucanGeneric NameFluconazoleUsual Dose200-800mg dailyOrdered DoseRoute &FrequencyAction ofMedicationAntifungalInhibits synthesis of fungal sterols, a necessary component of the cell membrane.Therapeutic Effect(s):Fungistatic action against susceptible organisms.May be fungicidal in higher concentrationsSide EffectsIncidence of adverse reactions is increased in HIV patientsCNS:headache, dizziness, seizuresGI:HEPATOTOXICITY, abdominal discomfort, diarrhea, nausea, vomitingDerm:EXFOLIATIVE SKIN DISORDERS INCLUDINGSTEVENS-JOHNSON SYNDROMEEndo:hypokalemia, hypertriglyceridemiaMisc:allergic reactions, includingANAPHYLAXISNursingConsiderationsAssess infected area and monitor CSF cultures before and periodically duringtherapy.Specimens for culture should be taken before instituting therapy. Therapy may be
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Drug Card,Alkaline phosphatase,liver function tests,Fluconazole,Stevens-Johnson syndrome