Week 7. Lecture 2.Contact Dermatitis.pdf - Objectives Contact Dermatitis PHARM 5210 NON-PRESCRIPTION PRODUCTS AND SELF-CARE WEDNESDAY CASSIUS HUDSON

Week 7. Lecture 2.Contact Dermatitis.pdf - Objectives...

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10/7/2016 1 P H A R M 5 2 1 0 N O N - P R E S C R I P T I O N P R O D U C T S A N D S E L F - C A R E W E D N E S D A Y O C T O B E R 1 2 , 2 0 1 6 C A S S I U S H U D S O N , P H A R M D P G Y 1 P H A R M A C Y P R A C T I C E R E S I D E N T U P M C P R E S B Y T E R I A N S H A D Y S I D E Contact Dermatitis Objectives ° Recognize common substances associated with irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD) ° Describe the cause and clinical presentation associated with irritant contact dermatitis and allergic contact dermatitis ° Identify appropriate candidates for self care of contact dermatitis ° Describe how to appropriately counsel a patient on the management of contact dermatitis Contact Dermatitis ° Condition characterized by inflammation, redness, itching, burning, stinging, vesicle, and pustule formation on dermal areas exposed to irritant and antigenic agents Allergic Contact Dermatitis: Accounts for 53% of workplace related reports Irritant Contact Dermatitis: Accounts for 21.6% of workplace related reports Plake. Handbook 17 th edition. 2012c Irritant Contact Dermatitis (ICD) ° Inflammatory reaction of the skin caused by exposure to an irritant ° May occur after a single exposure or multiple exposures to an irritant ° Proposed MOA ° Damage to epidermal cells by direct absorption ° Release of cytokines as a result of chemical exposure Plake. Handbook 17 th edition. 2012c Clinical Presentation of ICD Typically presents as dry or macerated, painful, cracked inflamed skin ** Everyone is different!! Exposure Inflammation Swelling itching Ulcer formation and localized necrosis Crusts over within days Plake. Handbook 17 th edition. 2012c Clinical Presentation of ICD Typically presents as dry or macerated, painful, cracked inflamed skin ** Everyone is different!! Exposure Inflammation Swelling itching Ulcer formation and localized necrosis Crusts over within days Plake. Handbook 17 th edition. 2012c
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10/7/2016 2 Factors that affect presentation of ICD ° Presence of existing skin conditions ° Quantity or concentration of substance ° Type of irritant ° Occlusive clothing ° Warmer weather and higher humidity Plake. Handbook 17 th edition. 2012c Treatment Goals ° Remove offending agent ° Relieve inflammation, tenderness and irritation ° Educate patient on self-management to prevent or treat recurrences Plake. Handbook 17 th edition. 2012c Non Pharmacologic Treatment ° Immediate washing to reduce contact time ° Cold compresses ° Barrier Creams ° Moisturizers ° Controversial Held E, et al. Effect of different moisturizers on SLS-irritated human skin. CD. 2001 Apr;44(4):229-34. Purpose: Evaluate 6 common moisturizers on recovery of ICD Methods: 36 volunteers: Placed 2 SLS patches on arm for 24h to induce ICD Applied moisturizer (2 of 6 types) 3x daily for 5 days on one arm Each volunteer tested 2 moisturizers (one on forearm/one on upper arm) Other arm was not treated Evaluated rash on days 1, 3 and 8 Results All 6 moisturizers were found to accelerate regeneration of the skin barrier Held E, Lund H, and Agner T. Effect of different moisturizers on SLS-irritated human skin. Contact Dermatitis. 2001 Apr;44(4):229-34.
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  • Fall '15
  • Contact dermatitis, Urushiol-induced contact dermatitis, allergic contact dermatitis, Barrier cream

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