6 Cardiac Ouput 2019.pptx - Anatomy Physiology II Cardiac Output Dr Heather Jones [email protected]ecom.edu 866-8133 Big Picture Mean Arterial Blood Pressure(MAP

6 Cardiac Ouput 2019.pptx - Anatomy Physiology II Cardiac...

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Anatomy & Physiology II : Cardiac Output Dr. Heather Jones [email protected] 866-8133
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Big Picture Mean Arterial Blood Pressure (MAP)
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Definition Cardiac output – total volume of blood pumped by the ventricles in one minute CO = HR x SV Control factors: Neurological Chemical
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Heart Rate Heart Rate – firing of the SA node (intrinsic rate, 100 bpm) Increase – Tachycardia > 100 bpm Decrease – Bradycardia < 60 bpm Chronotropic agents: Positive – increase Negative – decrease Control Mechanisms: 1. Neural 2. Chemical KNOW THIS SLIDE
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Heart Rate Neural Control – Autonomics Sympathetics – increase heart rate 1. Norepinephrine – NT 2. 1 -adrenergic receptors – SA node a. Increase current of F-type Na + channel b. Increase current of Ca 2+ channels Parasympathetics – decrease heart rate 1. Acetylcholine – NT 2. Muscarinic receptors – SA node a. Direct activation of K + ach channel b. Activate G i to inhibit adenylate cyclase KNOW THIS
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Heart Rate Neural Control:
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Baroreceptor Reflex Baroreceptor Reflex Stimulus: change in arterial blood pressure Baroreceptors: stretch receptors Short term regulation of BP
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