10 Gas Exchange Transport.pptx - Anatomy Physiology Gas Exchange:Transport Dr Heather Jones [email protected] 866-8133 Diffusion of Gases Gas exchange

10 Gas Exchange Transport.pptx - Anatomy Physiology Gas...

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Anatomy & Physiology :Gas Exchange:TransportDr. Heather Jones[email protected]866-8133
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Diffusion of GasesGas exchange between alveoli and bloodOxygen diffuses into the bloodCarbon dioxide diffuses into the alveoliDiffusion across the alveolar membraneThicknessSurface area
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Diffusion of GasesPartial pressures: what are the gradients?
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Diffusion of GasesHenry’s law: at an air water interface, the amount of gas which will dissolve is determined by the partial pressure of the gases in the air and the solubility in waterO2not very soluble in waterCO2more soluble in waterO2= 100 mm Hg * 0.03 mL O2/L/ mm HgO2= 0.3 mL O2/ 100 ml blood
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OxygenOxygen content in bloodPlasma alone vs. Plasma with hemoglobinPO2vs. O2ContentHemoglobinBinds four O2moleculesCooperative bindingDeoxyhemoglobin (Hb)Oxyhemoglobin (HbO)
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OxygenOxygen transport:1. Dissolved2.Bound to Hb
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OxygenHemoglobin saturation = O2bound to HbMaximal binding capacity of Hb to O2PO2determines binding affinityHigh at lungsSafety net in Hb situation
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