Drug Presentation2.pptx - enoxaparin (Lovenox) By Grace...

enoxaparin (Lovenox)
By Grace Alvesteffer

Actions
Is specifically active
against factor Xa and
thrombin
Prevents completion of
the coagulation cascade

Uses
•
To prevent deep vein thrombosis
•
Conjunction with warfarin to treat
•
Acute DVT, with or without
pulmonary embolus
•
ST- segment elevation MI
•
Prevents ischemic complications

Therapeutic Outcomes
•
Prevention of DVT after hip or knee
replacement surgery
•
Prevention of ischemic
complications of angina and MI

Premedication Assessments
•
Perform the following scheduled
lab tests before starting therapy:
•
CBC
•
Platelet count
•
Stool occult blood tests
•
Vitals signs

Dosage and Administration
•
Administer by deep subcutaneous injection into the
anterolateral or posterolateral abdominal wall every
12-24 hours
•
Rotate sites every 12 hours

Medication Safety Alert
•
DO NOT inject intramuscularly
•
Do Not expel the air bubble from the prefilled syringe
•
Dosage adjustment is required in patients with a
creatinine clearance of <30 ml/minute
•
Do NOT use in pts that are allergic to pork or pork
products

Common Adverse Effects