keycentraldogma

Keycentraldogma - More DNA and code questions to think about 1 Each amino acid has its own tRNA(some have several and each amino acid has its own

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More DNA and code questions to think about: 1. Each amino acid has its own tRNA (some have several) and each amino acid has its own code word in the messenger RNA (some have several). The adaptor (tRNA) is a translation device that receives (via a specific activating enzyme – aminoacyl tRNA synthetase) its specific amino acid. The adaptor (tRNA) also recognizes (via base pairing) the appropriate codon(s) in the message. So the critical players in translation are: I the amino acid X II its specific tRNA X III its specific activating enzyme (X) which recognizes X and tRNA X IV its specific X codon(s), which recognize the anti-codon of tRNA X Thus fidelity of translation depends on which of these specific interactions? a) I-II b) I-III c) I-IV d) II-III e) II-IV f) III-IV 2. In which of the interactions above is the principle of “two looks” used to avoid errors? Both III and IV (the incorrect tRNA can’t enter ???) – the aminoacyl tRNA synthetase double- checks that the correct amino acid
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3. In this table, mutations are classified according to their affect on three things. Choose terms from the list below to fill in the table. Be sure you understand the basis of each classification Several terms may fit in one blank. nonsense premature truncation base substitution amino acid substitution frameshift single base addition/removal missense transition a. unchanged e. truncation h. transversion b. base substitution f gibberish (extended errors) i. shorter c. synonymous substitution g amino acid substitution
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This note was uploaded on 07/03/2009 for the course BIS 64982 taught by Professor Comai during the Spring '09 term at UC Davis.

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Keycentraldogma - More DNA and code questions to think about 1 Each amino acid has its own tRNA(some have several and each amino acid has its own

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