LEC05a.ppt [Compatibility Mode]

LEC05a.ppt [Compatibility Mode] - 10/6/200 Announcements...

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Unformatted text preview: 10/6/200 Announcements Due to technical difficulties some students encountered, this weeks quiz will not count Quiz Oct 10 Two attempts No multiple answer or fill in the blank No multiple answer or fill in the blank By Friday, this past quiz and answers will be posted Protein structure What are the chemical building blocks and how are they put together? Are there any recurring structures? What does the protein look like in 3D? How many subunits are in a protein? How does protein structure relate to protein function? 10/6/200 Protein Structure Proteins are polymers made up of amino acids There are 20 different amino acids, each with different chemical properties (plus 2 variants) The 3D shape a protein adopts is determined by its sequence of amino acids The large number of 3D shapes that proteins can assume allows them to perform a wide range of functions Amino Acids Alanine 10/6/200 Hydrophilic Amino Acids Acidic amino acids R groups donate H readily in aqueous R groups donate H readily in aqueous environment and have a negative charge Basic amino acids acquire a H readily in aqueous environments and have a positive charge 10/6/200 Pyrrolysine Found in a few archaebacteria and eubacteria Coded by UAG (instead of a stop) Also considered basic Polar amino acids are uncharged but able to form H bond bonds Selenocysteine found Selenocysteine found in prokaryotes and eukaryotes UGA codon (instead of stop) 10/6/200 Non-polar amino acids Polypeptides Polypeptides are linear polymers of amino acids. Peptides usually contain less than about 20-30 amino acids....
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This note was uploaded on 07/08/2009 for the course LIFESCI LS 3 taught by Professor Paulolague during the Fall '09 term at UCLA.

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LEC05a.ppt [Compatibility Mode] - 10/6/200 Announcements...

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