midterm exam 1 key 08

# midterm exam 1 key 08 - a4 d LS 4.2 1't midterm April28...

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a4 d stude LS 4.2 1't midterm April 28, 2008 nt name student number Disc section (circle one) Wed at 11, Wed at 1, Wed at 3,Thur at 9, Thur at 11, Thur at 1 9 total bonus 1. Tall plants with yellow flowers crossed with short plants with white flowers yield all tall progeny with white flowers. Self crosses of these Fl yield these F2 out of 160 total progeny: Observed numbers expectednumbers chi-squaredvalues Tall white 100 7O Short white 21 30 Tall yellow 25 3 o Short vellow 14 /o TAB LE 4. I Crltlcal Chl Square Valuer (/oo -70)z/co = /oo /'ro = - !' / 'i7, -'t[y'. jzo . tt /!o 2'7 L;;- t,i''7eo = zr/to ,'P iir--rof /)o = *7 to . /' 4 * 6,L a. Write out a null hypothesis laying out a genetic explanation for these results. , 2 Sr.--- d^ /1r, /'h*-4 t Tt-cl ( at*z^--:A ) r*. s/'*'-f tt*{ -ffi (Jh) tr.- ,''tto; - z' &z**ol*-i-Ta',+'+/"*( b. List the numbers expected of your model in the space above, next to the observed numbers. Test your hypothesis by chi-squared analysis. Show all your work in calculating the chi-squared values and total. c. How many degrees of freedom are appropriate? .3 On this copy of the chi-squared table place a visable X at the location on the table of your chi-squared value (calculated above) and degrees of freedom. Draw an arrow from the X to the p value. What is the p value? /A f" 10 4 Degrees ol freedom Null Hypotherlr A((epted 0,99 0.90 o.50 Null Hypotheslr R lected o.05 0.01 o.ool x', trls I 0.02 45 2 3.44 6.64 I O.A3 ) 0^02 0.2r 'I .39 4 5.99 9.21 l:I.42 0.11 0,58 2.17 7.41 I1.35 r6.27 0.30 l,06 3.36 7.78 9.49 I l.2a la.4T 55 24 ,Q7 5.09 20.s2 d. Do you reject your null hypothesis? e. Based on your conclusions, predict you score 160 progeny. Tt/4 u.,l,k

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2. Cystic fibrosis is a rare condition. a. Using the pedigree below, what is the likely mode of inheritance? II III ,t) LL Circle correct answer. \9,/autosomal recessive ii. autosomal dominant iii. X linked recessive iv. X linked dominant v. either ii or iii. b. lf ll1 and l12 have 3 more children what is the chance no more than 1 of the additional 3 will have cystic fibrosis? Show work below and circle correct answer 3w ffi "lr/*-"Ll -e/dt = ,"7y'f , #hl^,( = i*- /r,U;z = z/q n/d 7 i. 10t64 (-15%) ii. 16t64 (-25%) iii.27)64 (-42%) @o'uo (-84%) c. ll14 and lll5 are hoping to start a family and come to you for advice. What first child will have cystic fibrosis? Show your work below and circle correct a llYJlxE-l t r
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## This note was uploaded on 07/08/2009 for the course LIFESCI ls 4 taught by Professor Merriam during the Winter '08 term at UCLA.

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midterm exam 1 key 08 - a4 d LS 4.2 1't midterm April28...

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