week 7 - Population 1 has 2000 AA individuals, 2000 Aa...

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Population 1 has 2000 AA individuals, 2000 Aa individuals and 6000 aa individuals. • What are the A and a allele frequencies? 1
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Population 1 has 2000 AA individuals, 2000 Aa individuals and 6000 aa individuals. • What number of each genotype is expected in this population with HWE (Hardy Weinberg equilibrium)? !! % )* + )* + ’ , -, , , % . , , - !$ % )* + )/ + 0 + ’ , -, , , % ( 0 , , - $$ % ’ , -, , , 1 2 -’ , , % ( -. , , 2
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Population 1 has 2000 AA individuals, 2000 Aa individuals and 6000 aa individuals. • Is this population in HWE? 34 3
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Population 1 has 2000 AA individuals, 2000 Aa individuals and 6000 aa individuals. • Assume mating happens at random for one generation. After one generation will the progeny population be in HWE? 567 4
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Assume population 2 is in HWE and has 9 Tay Sachs affected children out of 10,000 births. • What is the Tay Sachs allele frequency in this population, knowing it is autosomal recessive? * 8’ , , 5
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Assume population 2 is in HWE and has 9 Tay Sachs affected children out of 10,000 births. • What is the carrier frequency of Tay Sachs in this population? 6
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Assume population 2 is in HWE and has 9 Tay Sachs affected children out of 10,000 births. • Joe from population 2 has a sister with Tay Sachs; he wants to marry Sally from population 2. What can you advise them about the chance their first born child will have Tay Sachs? 0 8* 7
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Assume population 2 is in HWE and has 9 Tay Sachs affected children out of 10,000 births. • Erin, from population 2, wants to marry Ernie, from population 1 where it happens that only 1/10,000 births has Tay Sachs. What is their chance of having a first child with Tay Sachs? * 8 ’ , -, , , 8
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1 in 12 males has some form of red-green colorblindness, an X-linked trait. • What is the colorblindness allele frequency? ’ 8 ’ 0 9
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1 in 12 males has some form of red-green colorblindness, an X- linked trait. • Males form only half the population. What is the chance a female will be colorblind? ’ 8’ 0 + ’ 8’ 0 % ’ 8 ’ ( ( 10
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The ABO blood group alleles have frequencies of .20, .10 and .70 for the I[A] allele, the I[B] allele, and the i allele, respectively, in a populaton . • What is the expected number of type A among 10,000 individuals in this population? :)0 + )0 ; )0 + )/ + 0 < + ’ , -, , , % * 0 , , 11
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mutants. The experiment started with mixed infections, 2 mutants at a time, on E. coli strain B; the progeny were plated on E. coli strain K12(l). 1 2 3 4 1 - 7 mu 0 4 mu 2 - 5 mu 3 mu 3 - 2 mu 4 - Does the first infection represent permissive or restrictive conditions? =6>? @77@A6
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This note was uploaded on 07/08/2009 for the course LIFESCI ls 4 taught by Professor Merriam during the Winter '08 term at UCLA.

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week 7 - Population 1 has 2000 AA individuals, 2000 Aa...

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